Published:11:45 AM EDT
A Brazilian researcher has found that the most commonly used drugs used to treat erectile dysfunction, called sildenafil, can lead to liver damage. The researchers used mice to study whether these drugs can cause liver damage.
The research, published in the journal, looked at more than 1,000 mice before and after they were given the drugs, known as Viagra and Cialis.
Researchers tested the drugs in healthy mice, then treated the mice with sildenafil, which they believe causes liver damage. After they took the drug, they found no signs of damage to the liver.
The researchers then compared the liver to human sildenafil-treated mice. The liver cells were normal, but there were signs of damage to the liver.
The researchers found no difference in the amount of liver damage between the sildenafil-treated and the untreated mice. This means the drugs were safe for those who took them.
The drugs were found to be safe, but scientists believe the damage is caused by the drug's inhibition of an enzyme called phosphodiesterase 5 (PDE5).
The researchers said that the liver is a key organ in the body that controls blood pressure and heart function. Sildenafil inhibits the PDE5 enzyme.
It's not known if the drugs cause liver damage in humans. However, the study is one of the only studies that has been done to see if sildenafil could cause liver damage.
Dr. David Nissen, a research fellow at the University of St. Andrews in London, says the drug has shown promise in the research. "It's a very interesting finding," he says.
"It is very important that we take a closer look at the underlying cause of this problem."
The researchers found that sildenafil caused a significant reduction in liver enzymes, which means the liver is less efficient at producing this compound.
They added that some of the sildenafil-treated mice also had abnormal results when they took the drugs, which means their liver is less efficient at producing the compound.
The research was published in the journal's, with the help of an editorial.
Copyright © 2025 CBS News - Last modified: 04/05/2022
All rights reserved. Republication and distribution in any other form of medical or scientific media are not permitted.IMPORTANT NOTE: This is the latest study to investigate the relationship between sexual dysfunction and erectile dysfunction.
The results, reported in the journal, are based on a pilot study of mice and humans to test the effects of sildenafil on liver cells.
Researchers from the University of St. Andrews in London, have now found that the drugs can cause liver damage.
The results were published in the journal.
The researchers used mice to test whether these drugs can cause liver damage.The research was published in the journal'sJournal of Sexual Medicine(J Sex Med).The research was based on a pilot study of mice and humans to test the effects of sildenafil on liver cells. The mice and humans were then treated with sildenafil, which researchers believe could cause liver damage.The researchers, who did not return a request for comment, say they found no difference in liver cells between the sildenafil-treated and the untreated mice. But they added that they believe that the liver is a key organ in the body that controls blood pressure and heart function.
The research was published in.Scientists from the University of St.
Andrews in London, have found that the drugs can cause liver damage.
The research was published in theForum Thread Title:What Does Viagra Do for You?
NickName123 asked:Hey everyone! I've been reading your posts about Sildenafil and Vigorex for the past few days. Can you shed some light on what these drugs actually do for you?
DocWiff asked:Hi NickName123! I've heard that you're always wondering what the difference between these drugs is?
Hey, DocWiff! Thanks for your reply! I'll be adding a bit more details below for your detailed answers. Let me know if you have any more questions or need more information on this topic. Thanks again!
What Is the Effectiveness of Viagra and Vigorex in Treating Erectile Dysfunction?
I've heard that you're always asking if these drugs are effective for you. Do you have any specific questions?
I've been reading your posts regarding Sildenafil and Vigorex for the past few days.
Hi DocWiff!
Here is a closer look at the differences between these drugs. Please keep in mind that you may not be able to find these anywhere in the U. S., and you can still get them on the Internet. Also, you might need to go to a pharmacy or get a prescription from someone who might be able to get them. In any case, let me know if you have any more questions or need more information on this topic.
I'll be adding more details for your detailed answers.
Here's a closer look at the differences between these drugs.
Viagra is a FDA approved prescription medication for the management of erectile dysfunction. It helps enhance blood flow, supporting erectile function during sexual activity.
Viagra 50mg Tablet can be taken with or without food but should always be used as directed by your doctor. For best results, take it approximately one hour before planned sexual activity. While the time it takes to work may vary from person to person, it usually starts acting within 30 minutes to an hour. This medicine works only when there is sexual stimulation. Do not exceed the recommended dose of one tablet in 24 hours.
Avoid alcohol consumption while taking this medicine, as it can increase the likelihood of experiencing side effects such as dizziness or headache and may decrease the effectiveness of Viagra Tablet.
It is essential to avoid using it with nitrate-based medications (commonly prescribed for chest pain or angina) as this combination can cause serious health risks. Additionally, do not use Viagra 50mg Tablet if you have severe heart or liver conditions, have recently experienced a heart attack or stroke, or have very low blood pressure. Always inform your doctor about your medical history before starting this medication.
The most common side effects of Viagra include flushing (a warm sensation), headache, dizziness, blurred vision, muscle pain, indigestion, and rash. If these effects persist or become bothersome, consult your doctor for advice. They may adjust your dosage or suggest an alternative treatment. Patients are advised to seek immediate medical attention if an erection lasts more than 4 hours, as priapism can cause permanent damage to the penis.
What is Viagra (sildenafil)Viagra is a medication commonly prescribed to treat erectile dysfunction. It works by enhancing the blood flow to the penis, which can help enhance erections during sexual stimulation. Viagra 50mg Tablet is a nitrate-based medication that can lower blood pressure and increase the time it takes to achieve an erection.
Viagra 50mg Tablet is a prescription medication, and a patient should obtain it by prescription from their doctor. There are various methods to get and maintain maximum benefits from Viagra, including participation in supervised clinical trials (also known as controlled trials) and participation in clinical trials. There are various strengths of Viagra, including 25 mg, 50 mg, and 100 mg. Taking Viagra 50mg Tablet with a heavy meal can delay its onset of activity until tcessive alcohol intake is controlled.
The mechanisms by which Viagra can improve erectile function are unknown, but it is considered a safe medication for use in individuals with heart and liver conditions. Your doctor may suggest ways to minimize your risk for developing cardiovascular issues or adjust your dosage during treatment. Viagra 50mg Tablet is taken orally within 30 minutes to an hour before sexual activity, with or without food. While the time it takes to work may vary from person to person, it usually starts working within 30 minutes to an hour. While the time it takes to work usually runs the gamut from 30 minutes to an hour, it usually takes between 30 minutes and 60 minutes to start working.
It is common to experience headaches, dizziness, muscle pain, indigestion, and decreased libido in response to Viagra 50mg Tablet. Additionally, Viagra 50mg Tablet users can experience depression, a rare but progressive condition that affects the sexual ability of men with varying degrees of sexual dysfunction. This condition typically progresses to a partial or complete stoppage of the menstrual cycle. The affected man most likely has experienced ED after taking Viagra 50mg Tablet, and Viagra 50mg Tablet can cause serious side effects, including dizziness, low libido, and changes in the menstrual cycle.
Consult your doctor if you are experiencing any of the listed side effects, and inform them about any before starting Viagra. Viagra 50mg Tablet is not recommended for use in women. Viagra 50mg Tablet should not be taken by men while they are taking nitrates, as this combination can cause serious health risks. Additionally, avoid use during the first three months of menopause as this combination can cause serious side effects, including breast cancer and osteoporosis.
The most common side effects of Viagra 50mg Tablet are flushing, headache, dizziness, blurred vision, muscle pain, indigestion, and rash. These side effects are usually mild, and usually do not require your regular medical supervision. In most cases, Viagra 50mg Tablet users experience mild to moderate side effects that last for a few days, allowing you to take necessary precautions. However, if Viagra 50mg Tablet side effects persist, you should consult a healthcare professional.
Men in the UK will be able to buy Viagra over the counter after consulting with a pharmacist and without a prescription for the first time today.
ViagraConnect manufacturer, Pfizer, estimates more than a fifth of men aged over 18 in Britain suffer from erectile dysfunction, but almost half of those over 40 have not sought medical help.
The erectile dysfunction drug will be available in 14,000 stores across Britain and via pharmacy websites.
The tablets will be available exclusively from Boots until 10 April.
Those aged 18 and over will be able to buy the tablets following a conversation with a pharmacist or after filling out an online form. Men can ask to speak to a pharmacist in a private consultation room if preferred.
The pharmacists will determine whether treatment is appropriate for the patient and give advice on erectile dysfunction, usage of the medicine and potential side effects. They will advise men to consult with their doctor no less than six months after buying Viagra so that any potential underlying conditions such as diabetes, high blood pressure, or heart disease can be investigated.
A Boots spokesperson said that the man affected by erectile dysfunction should buy the drug themselves wherever practically possible.
Men with severe heart problems, those at high risk of heart problems, liver failure, kidney failure, strokes or those taking certain other medicines, will still need to be prescribed the drug under the supervision of a doctor.
A four-pack of the tablets will cost £19.99 and an eight-pack £34.99.
Men who buy it will be advised that they can take a 50 mg tablet an hour before having sex, but should not use more than one pill a day.
Viagra is is already available as an NHS prescription free of charge for those eligible not to pay for their prescriptions.
The pharmacist will decide how many packs will be supplied in a transaction.
The Medicines and Healthcare products Regulatory Agency (MHRA) announced in November it was to steer men away from buying the tablets from. In 2016 £17m worth of unlicensed and counterfeit Viagra was seized.
Kristie Sourial, Pfizer’s medical manager, said: “It’s important to remember that erectile dysfunction is a medical condition, and that the impact often goes beyond the physical symptoms – it can lead to men feeling anxious, depressed and lacking in confidence.
“Our hope is that the availability of Viagra Connect in pharmacies will encourage men who do nothing about their erectile dysfunction to seek help, and encourage those who are inclined to seek help to do so sooner.”
Viagra tablets will be available for sale following a private consultation, she is quoted as saying:.How the online consultation has been established is not always guaranteed.Read more
We have seen potential opportunity to purchase Viagra online in avertising which has been approved as “oroughness “ and “form interest-y” " so we can give you an opportunity to try and buy some tablets “.
Sildenafil citrate, commonly known as Viagra, is a medication used to treat erectile dysfunction (ED) in men. It works by improving blood flow to the penis, which helps men achieve and maintain an erection. While Viagra is commonly used to treat ED, it's not the only option available. Other treatments for ED include lifestyle changes, such as weight loss, stress reduction, and medical treatments such as hormone replacement therapy (HRT). If you're considering using Viagra for ED, there are several factors to keep in mind before making a purchase. These include the severity of your ED, the type of ED you have, and your medical history. In addition to the severity of your ED, your doctor may also need to know about any other medications you're taking. Some medications may be risky for you if you take them too soon after you've taken an ED medication. Some of these medications may cause side effects, including dizziness, headaches, and changes in vision. It's important to discuss any concerns with your healthcare provider before starting Viagra or any other treatment for ED. In conclusion, Viagra is a safe and effective treatment for erectile dysfunction and should be used as directed. However, it's important to talk to your doctor about any other medications or supplements you're taking before starting Viagra or any other treatment for ED.